Sterile continuous bags enable the continuous, aseptic transfer of powder and other materials out of an isolator, hopper or process vessel without ever breaking the sterile barrier. By sealing and cutting sections of the bag at intervals, material can be removed continuously while the remaining bag stays sterile. Wuxi Harmake Technology Co., Ltd. manufactures sterile continuous bags for pharmaceutical and biopharmaceutical processing.

 

 

A sterile continuous bag is a long sleeve of sterile single-use film attached to a process port. As material flows into the bag, the filled section is heat-sealed across the sleeve and cut off for removal, while the next section remains attached and sterile. This allows continuous operation, faster processing and safer handling of potent materials.

 

 

 

●The bag sleeve is connected to the isolator or equipment port

●Material fills the bag under aseptic conditions

●A heat sealer creates a seal across the filled section

●The filled section is separated while the sterile barrier is maintained

●The process repeats continuously for high-throughput operation

 

 

 

●Continuous operation with no repeated opening of the process barrier

●Complete aseptic containment from start to finish

●Reduced product loss and improved operator safety

●Compatible with potent and hazardous material handling

●Eliminates the need for cleaning and sterilization of transfer equipment

 

 

 

Our sterile continuous bags are manufactured from USP Class VI biopharmaceutical film with low dissolution, high cleanliness and strong mechanical performance. Each bag is 100% integrity tested to ensure a reliable sterile barrier, and products are supplied sterile for direct use.

 

 

 

Sterile continuous bags are widely used in modern pharmaceutical manufacturing:

●Powder charging and discharge from isolators

●Continuous transfer in oral solid dosage (OSD) manufacturing

●Handling of potent APIs and highly active compounds

●Aseptic filling line waste and product collection

●Continuous bioprocess operations

 

 

 

Wuxi Harmake Technology provides high-quality sterile and dust-free single-use products backed by ISO9001 and ISO13485 certified CGMP manufacturing. With one-stop planning and service, we help you integrate sterile continuous bags into your process efficiently. Contact us for a solution tailored to your line.